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Category:American music awards Category:American music video awards Category:Awards established in 1959 Category:Grammy Awards Category:Music of Los AngelesBradykinin and its receptors in airway mucosa. Bronchial mucosal hyperresponsiveness (BHR) to chemical or histamine challenge in healthy subjects is closely related to the presence of an inflammatory cell infiltrate in the submucosa. This leads to the hypothesis that inflammatory mediators or receptors might be responsible for this abnormality. Bradykinin has been suggested as a possible mediator of BHR. Since the bradykinin B2 receptor has been reported to be present on inflammatory cells and is functionally coupled to adenylate cyclase, it is a candidate for mediating the effect of bradykinin. The aim of the present study was to investigate the presence of bradykinin B2 receptors and bradykinin in the airway mucosa of healthy subjects and patients with allergic asthma. Indirect immunofluorescence was used for the detection of bradykinin B2 receptor in frozen sections of normal human nasal mucosa. In addition, bradykinin was measured in bronchial biopsies by radioimmunoassay. Bradykinin B2 receptor was found to be present in both normal and allergic mucosa. Bradykinin was present at significantly higher concentrations in the submucosa of the allergic mucosa as compared to the mucosa of healthy subjects. However, there was no significant difference between the two groups when measurements were performed in all mucosa (mucosa as well as submucosa). This study demonstrates that bradykinin B2 receptors are present in the human airway mucosa and that the concentration of bradykinin is raised in asthmatic airway mucosa. However, the major source of bradykinin in the airway mucosa does not seem to be the epithelial cells. The possibility that bradykinin may mediate part of the BHR in allergic asthmatics and is involved in the pathophysiology of asthma remains to be determined.Q: Get files of a directory without processing all of them I'm trying to retrieve files and directories from a directory (with specific extensions) and then send them to a directory via ftp command, but for some reason my code is processing the files that are inside a directory and sending them to the other one. This









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